Dionpharma

Use of specialists : DION Perfect white advance fairness

DION Perfect white advance fairness
A powerful cream that unifies the skin colour by supressing melanin production , it visibly brightens and unifies the kin in 2 months by attenuating pigmentation spots .
It makes the skin lighter , brighter , and radiant, by protects against UV rays
DION PERFECT WHITE cream rich in 2% α-Arbutin , ChromaBRIGHT® , Vit E & B3 , Titanium dioxide

2% ALPHA ARBUTIN (WHITENING TYROSINASE INHIBITOR )
0.1% ChromaBRIGHT (WHITENING TYROSINASE INHIBITOR )
VIT E (WHITENING AND ANTIOXIDANT )
VIT B3 (ANTIOXIDANT WHITENING )
TITANIUM DIOXIDE (SUNSCREEN)
INDICATIONS
⦁ Melasma
⦁ Post pregnancy melasma
⦁ Age spots
⦁ sun spots.
⦁ Hormonal HYPERPIGMENTATION
⦁ Spots produced by using photosensitive products
(make up products, perfumes and drugs).
⦁ HYPERPIGMENTATION arising from aggressive cosmetic. treatments (peeling, laser and cryotherapy)

Application

•First gently wash and dry your face

•Apply a thin layer of Perfect White

•Massage it gently until it gets fully absorbed into your skin

•The cream should be used in this way twice times a day.

Warnings

•Dion anti-wrinkle® is for EXTERNAL USE ONLY.
•Avoid contact with the eyes
•keep away of children’s reach

Study

ChromaBRIGHT study

2% ALPHA ARBUTIN study

1- Effects of a-Arbutin on melanin production in cultured human melanoma cellsα-Arbutin showed
dose-dependent inhibition of melanin production in cultured human melanoma cells without affecting cell viability.

2- Clinical Study of Efficacy for Skin-LighteningWe evaluated skin-lightening effects by clinical study involving
60-human volunteers.
⦁ % α-Arbutin

RESULT: Better skin-lightening efficacy than the competitive ingredients, such as Arbutin-β, Kojic acid and Hydroquinone

Duration: 1 month.

Effects of α-Arbutin were sustained during the study period, three months.

Study subject : 20 persons / group
Treatment : treated twice daily with test cream containing 1 % active ingredient
Evaluation : objectively by colorimetric at M0 and M1

3- Clinical Study of Efficacy for Prevention of Pigmentation Induced by Ultraviolet Irradiation We examined the inhibitory effect of α-Arbutin toward pigmentation induced by ultraviolet irradiation.
as compared with a control cream preparation, a cream preparation containing 2.0 % α-Arbutin had a significant degree of ability to suppress pigmentation induced by ultraviolet irradiation, in the same manner as a cream preparation containing 3.0 % sodium ascorbylphosphate.
It was also confirmed that a cream preparation containing 1.0 % α-Arbutin had a tendency to suppress melanogenesisinduced by ultraviolet irradiation, although this effect was weak as compared with that of the cream preparation containing 2.0 % α-Arbutin and the cream preparation containing 3.0 % sodium ascorbylphosphate

Study subject : 23 persons
Treatment : treated twice daily with test cream preparations
UV-irradiation : one time (the first day of the test)
Evaluation: objectively by colorimetrybefore (week 0) and at weeks 1, 2, and 3.

Niacinamide B3 study

Alpha-Tocopherol(VitE) study

references:

Links :
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